Medicare Enrolled
Dr. Matthew Holtzman, M.D.
Clinical Neurophysiology Physician · Wayne, MI
Practice pattern: Mixed Practice
— Diverse clinical practice across multiple procedure types
Speaking/Promotional
Very High
DATA COVERAGE
Data in 4 of 4 federal sources
Measures public federal data availability — not provider quality
Informational, not a quality rating.
This page presents federal public records about Dr. Holtzman from CMS (NPPES, Open Payments, Medicare Provider Utilization, PECOS). It is not medical advice, an endorsement, or a judgment of clinical quality. Always consult the provider directly and a licensed clinician for medical decisions. Read methodology →
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What this data tells you about Dr. Holtzman
Dr. Matthew Holtzman is a clinical neurophysiology physician in Wayne, MI, with 19 years of NPI registration. Based on federal Medicare data, Dr. Holtzman performed 11,229 Medicare services across 491 unique beneficiaries.
Between the years covered by Open Payments, Dr. Holtzman received a total of $1,527,753 from 110 pharmaceutical and/or device companies across 4368 individual payments. These payments are legal, publicly disclosed under the federal Sunshine Act, and common in clinical neurophysiology physician. The majority of payments are for speaking programs and promotional activities, reflecting participation in industry-sponsored events. Patients may wish to discuss these relationships with their provider.
The Data Coverage level for Dr. Holtzman is Very High — reflecting how much public federal data is available about this provider. Patients are encouraged to use this data as one of several factors when choosing a healthcare provider.
✓ 19 years in practice
▲ Top 7% volume in MI
$1,527,753 industry payments
Medicare Practice Summary
Medicare Utilization ↗11,229
Medicare services
Top 7% in MI for clinical neurophysiology physician
491
Unique beneficiaries
$11
Avg. Medicare payment
Medicare patients only (65+ / disabled) · How to read this →
~591 Medicare services per year of practice
Top procedures by volume
Ranked by number of services performed for Medicare patients. Avg. submitted charge is what the provider billed; avg. Medicare payment is what CMS paid.
| Procedure | Volume | Avg. paid | Avg. submitted |
|---|---|---|---|
| Botox injection, per unit An injection of onabotulinumtoxinA, a medication used to temporarily relax muscles or reduce gland activity. The dose is measured in units, with this code representing a single unit administered. |
10,300 | $5 | $15 |
| Office visit, established patient (30-39 min) A follow-up office visit for an existing patient lasting between 30 and 39 minutes. The visit involves medical evaluation and management of the patient's condition. |
407 | $90 | $212 |
| Steroid injection (triamcinolone) A 10 mg injection of triamcinolone acetonide, a corticosteroid medication. This code specifies the drug and dosage administered. |
115 | $1 | $15 |
| Electromyography of arm or leg muscles A test that measures the electrical activity in the muscles of the arm or leg using a needle electrode. It helps evaluate the health of muscles and the nerve cells that control them. |
101 | $76 | $240 |
| New patient office visit (45-59 min) An initial office visit for a new patient lasting between 45 and 59 minutes. This code covers the total time spent by the physician or qualified healthcare professional on the date of the encounter. |
71 | $115 | $315 |
| Office visit, established patient (20-29 min) An office visit for an existing patient lasting between 20 and 29 minutes. The visit involves medical evaluation and management of the patient's condition. |
70 | $65 | $140 |
| Nerve conduction study, 9-10 studies A diagnostic test that measures how well nerves send electrical signals. It involves performing 9 to 10 separate nerve conduction studies to evaluate nerve function. |
51 | $164 | $900 |
| Bilateral facial and neck nerve muscle paralysis injection Injection of a chemical agent to paralyze muscles in the face and neck on both sides. |
32 | $126 | $400 |
| Needle measurement of electrical activity in muscle with injection of chemical for paralysis of nerve muscle | 32 | $59 | $165 |
| Trigger point injection, 3 or more muscles Injection of medication into three or more specific muscle trigger points to relieve pain. |
31 | $41 | $120 |
| Awake and drowsy EEG A test that records electrical activity in the brain while the patient is awake and drowsy. |
19 | $301 | $781 |
How to read this data: This reflects Medicare patients only (typically 65+). Payment amounts are what Medicare paid the provider, not your out-of-pocket cost. A higher procedure volume generally indicates more experience with that procedure.
Industry Payment Transparency
Open Payments through 2024 ↗$1,527,753
Total received (2018-2024)
Avg $218,250/year across 7 years
Top 7% in MI for clinical neurophysiology physician
A higher payment rank reflects disclosed industry relationships (consulting, research, speaking) common among subspecialists — not wrongdoing.
110
Companies
4,368
Individual payments
All payments are legal and publicly reported · Not evidence of wrongdoing · How to interpret →
Payment profile
Industry payments classified by relationship type. Not all payments are equal — research and consulting reflect different relationships than speaking programs or meals.
Speaking / Promotional
Speaker programs, honoraria, and industry-sponsored educational events
$1,432,807 (93.8%)
Consulting
Expert advisory fees, typically reflecting recognized clinical expertise
$50,648 (3.3%)
Meals & Travel
Food, beverages, travel, and lodging — typically low-value
$44,298 (2.9%)
Payment trend by year
Annual totals from pharmaceutical and medical device companies.
2024
$136,172
2023
$186,643
2022
$285,135
2021
$296,444
2020
$151,624
2019
$242,587
2018
$229,149
Payments by company (2024)
Consulting
Speaking
Meals & Travel
Research
ABBVIE INC.
$86,616
CATALYST PHARMACEUTICALS, INC.
$38,710
SK Life Science, Inc.
$4,996
Medtronic, Inc.
$2,832
Genentech USA, Inc.
$263
Celgene Corporation
$262
Takeda Pharmaceuticals U.S.A., Inc.
$229
Ipsen Biopharmaceuticals, Inc
$205
LivaNova USA, Inc.
$200
ARGENX US, INC.
$196
Lundbeck LLC
$176
JAZZ PHARMACEUTICALS INC.
$173
Alexion Pharmaceuticals, Inc.
$150
Genentech, Inc.
$148
MITSUBISHI TANABE PHARMA AMERICA, INC.
$140
UCB, Inc.
$101
Teva Pharmaceuticals USA, Inc.
$88
ANI Pharmaceuticals, Inc.
$87
Merz Pharmaceuticals, LLC
$85
Amneal Pharmaceuticals LLC
$81
ACADIA Pharmaceuticals Inc
$78
REVANCE THERAPEUTICS, INC.
$69
GENZYME CORPORATION
$68
Azurity Pharmaceuticals, Inc.
$43
Vanda Pharmaceuticals Inc.
$31
Bausch Health US, LLC
$29
Aucta Pharmaceuticals, Inc.
$25
Biogen, Inc.
$24
ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.)
$23
Grifols USA, LLC
$15
IDORSIA PHARMACEUTICALS US INC
$15
Forte Bio-Pharma LLC
$14
Top 3 companies account for 95.7% of 2024 payments
All-time payments by company (2018-2024) ›
ABBVIE INC.
$337,506
Eisai Inc.
$203,717
EISAI INC.
$155,802
AbbVie Inc.
$132,474
SK Life Science, Inc.
$88,373
Medtronic Vascular, Inc.
$71,791
Grifols USA, LLC
$58,691
Genentech USA, Inc.
$48,171
Allergan, Inc.
$47,853
Biohaven Pharmaceuticals, Inc.
$46,633
Teva Pharmaceuticals USA, Inc.
$44,895
CATALYST PHARMACEUTICALS, INC.
$40,534
Acorda Therapeutics, Inc
$23,112
Biohaven Pharmaceutical Holding Company Ltd.
$22,947
Mallinckrodt LLC
$21,748
E.R. Squibb & Sons, L.L.C.
$21,443
Celgene Corporation
$19,931
Sunovion Pharmaceuticals Inc.
$17,517
Supernus Pharmaceuticals, Inc.
$17,386
Allergan Inc.
$15,191
Medtronic, Inc.
$13,941
Horizon Therapeutics plc
$12,334
Catalyst Pharmaceuticals, Inc.
$10,484
LivaNova USA, Inc.
$7,629
AbbVie, Inc.
$7,139
Lundbeck LLC
$6,264
ACADIA Pharmaceuticals Inc
$5,596
Mallinckrodt Enterprises LLC
$3,464
Bausch Health US, LLC
$2,865
Egalet US Inc
$1,802
Abbott Laboratories
$1,739
Genentech, Inc.
$1,629
Medtronic USA, Inc.
$1,265
F. Hoffmann-La Roche AG
$1,200
UCB, Inc.
$976
Amgen Inc.
$929
GENZYME CORPORATION
$927
Ipsen Biopharmaceuticals, Inc
$699
Alexion Pharmaceuticals, Inc.
$638
JAZZ PHARMACEUTICALS INC.
$499
EMD Serono, Inc.
$499
Neurelis, Inc.
$465
Neurocrine Biosciences, Inc.
$455
Amneal Pharmaceuticals LLC
$450
Endo Pharmaceuticals Inc.
$418
ARGENX US, INC.
$415
PFIZER INC.
$381
Takeda Pharmaceuticals U.S.A., Inc.
$375
CSL Behring
$351
US WorldMeds, LLC
$331
Merz North America, Inc.
$319
Avanir Pharmaceuticals, Inc.
$307
Integra LifeSciences Corporation
$301
Biogen, Inc.
$300
Merz Pharmaceuticals, LLC
$294
ITI, Inc.
$292
TG THERAPEUTICS, INC.
$283
UPSHER-SMITH LABORATORIES LLC
$213
Alnylam Pharmaceuticals Inc.
$205
MITSUBISHI TANABE PHARMA AMERICA, INC.
$201
Janssen Pharmaceuticals, Inc
$198
Promius Pharma LLC
$161
ANI Pharmaceuticals, Inc.
$154
HARMONY BIOSCIENCES LLC
$151
Mallinckrodt Hospital Products Inc.
$145
AstraZeneca Pharmaceuticals LP
$138
Saol Therapeutics Inc.
$137
Nevro Corp.
$133
TG Therapeutics, Inc.
$129
Jazz Pharmaceuticals Inc.
$128
Harmony Biosciences LLC
$104
Sumitomo Pharma America, Inc.
$100
Vertical Pharmaceuticals, LLC
$91
Assertio Therapeutics, Inc.
$89
Greenwich Biosciences, Inc.
$88
Zyla Life Sciences, Inc.
$79
Mitsubishi Tanabe Pharma America, Inc.
$72
MERZ NORTH AMERICA, INC.
$69
REVANCE THERAPEUTICS, INC.
$69
Kyowa Kirin, Inc.
$63
Scilex Pharmaceuticals Inc.
$63
Upsher-Smith Laboratories LLC
$59
Aprecia Pharmaceuticals, LLC
$56
Impax Laboratories, Inc.
$51
Otsuka America Pharmaceutical, Inc.
$44
Azurity Pharmaceuticals, Inc.
$43
Zyla Life Sciences
$41
Axsome Therapeutics, Inc.
$38
ORPHALAN INC
$38
Novartis Pharmaceuticals Corporation
$33
Avion Pharmaceuticals
$31
Vanda Pharmaceuticals Inc.
$31
Akcea Therapeutics, Inc.
$28
Alfasigma USA, Inc.
$28
Lilly USA, LLC
$27
Aucta Pharmaceuticals, Inc.
$25
Octapharma USA, Inc.
$25
Collegium Pharmaceutical, Inc.
$24
ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.)
$23
Corium, LLC
$22
Bio Products Laboratory USA, Inc.
$20
AQUESTIVE THERAPEUTICS, INC.
$19
Amylyx Pharmaceuticals, Inc.
$19
Exeltis, USA Inc.
$16
IDORSIA PHARMACEUTICALS US INC
$15
Forte Bio-Pharma LLC
$14
Adamas Pharmaceuticals, Inc.
$13
GRT US Holding, Inc.
$13
Currax Pharmaceuticals LLC
$12
Retrophin, Inc.
$1
Top 3 companies account for 45.6% of all-time payments
Associated products mentioned in payments ›
(820) Cholbam · ACTHAR · ADUHELM · AJOVY · AMPYRA · APLENZIN · APOKYN · APTIOM · AUBAGIO · AUSTEDO · Adlarity · Aimovig · Arctic Front · Austedo XR · Auvelity · BOTOX · BOTOX - NEUROLOGY · BOTOX - SPASTICITY · BOTOX COSMETIC · BOTOX THERAPEUTIC · BRILINTA · BRIUMVI · Briviact · CAPLYTA · CHANTIX · COMIRNATY · CONTRAVE · COPAXONE · CUTAQUIG · CUVRIOR · Cenobamate · DAXXIFY · DUOPA · DYSPORT · Dayvigo · Dhivy · Duopa · Dysport · ELYXYB - celecoxib · EMGALITY · EPIDIOLEX · Enspryng · Epidiolex · FIRDAPSE · FYCOMPA · Fycompa · GAMMAGARD · GILENYA · GOCOVRI · GRALISE · Gammaplex · Gamunex-C · HETLIOZ · HORIZANT · HYQVIA · Hizentra · INBRIJA · INGREZZA · Infinity DBS Pulse Generators · Integra · KYNMOBI · LINQ II · LIORESAL · LOOP · LYRICA · Leqembi · Lioresal (baclofen) · Lioresal Intrathecal (baclofen injection) · MAVENCLAD · MIGRANAL · MYOBLOC · Mavenclad · Motpoly XR · MyCareLink · NALOCET · NASCOBAL · NEXVIAZYME · NORTHERA · NOURIANZ · NUEDEXTA · NUPLAZID · NURTEC ODT · Nayzilam · Neuromodulation Dspsbls and Accs · None · OCREVUS · OCTAGAM IMMUNE GLOBULIN (HUMAN) · ONFI · ONGENTYS · ONPATTRO · OSMOLEX ER · OXTELLAR XR · Ocrevus · Ocrevus Zunovo · Ongentys · PANZYGA · PONVORY · PURIFIED CORTROPHIN GEL · Ponvory · Privigen · QELBREE · QUDEXY XR TOPIRAMATE EXTENDED RELEASE CAPSULES · QULIPTA · QUVIVIQ · Qutenza · RADICAVA · RELYVRIO · REXULTI · RYTARY · Radicava · Reveal LINQ · Reveal XT · Rystiggo · SKYCLARYS · SOLIRIS · SPINRAZA · SPRIX · SUNOSI · SYMPAZAN · Senza · Skyclarys · Soliris · Solitaire · Spritam · TEGSEDI · TOSYMRA · TOSYMRA SUMATRIPTAN NASAL SPRAY · TROKENDI XR · UBRELVY · ULTOMIRIS · UPLIZNA · VALTOCO · VIBERZI · VNS - Sentiva · VNS THERAPY SENTIVA MODEL 1000 GENERATOR · VNS Therapy · VNS Therapy SenTiva Model 1000 Generator · VRAYLAR · VYALEV · VYEPTI · VYVGART · VYVGART HYTRULO · Vimpat · Wakix · XARELTO · XCOPRI · XEOMIN · XYREM · XYWAV · Xadago · Xembify · Xeomin · ZEMBRACE SYMTOUCH · ZEPOSIA · ZIPSOR · ZTLido · ZTLido 30 POUCH in 1 CARTON 1 PATCH in 1 POUCH · Zembrace
Should you be concerned? Payments from pharmaceutical and device companies are legal and common — 57% of U.S. physicians receive at least one. They often reflect legitimate consulting, research, or education. What matters is whether a recommended drug or device appears in your doctor's payment records. If so, consider asking your doctor about it. How to interpret this data →
The majority of payments (94%) are for speaking programs and promotional activities, which reflect participation in industry-sponsored educational or marketing events. This is common in clinical neurophysiology physician and does not inherently indicate bias, but patients may wish to be aware. Total industry engagement is in the top 7% for clinical neurophysiology physician in MI.
Geographic Context
Clinical neurophysiology physicians within 10 mi
12
Per 100K population
0.7
County median income
$59,521
Nearest hospital
COREWELL HEALTH WAYNE HOSPITAL
0.0 mi
0.0 mi
Data Sources
| Provider Registry | ✓ NPPES | Weekly updates |
| Medicare Enrollment | ✓ PECOS | Monthly updates |
| Practice Data | ✓ Medicare Util. | Annual (CY lag) |
| Industry Payments | ✓ Open Payments | CY 2024 |
| Disciplinary History | — Not public | N/A |
This provider has data in 4 of 4 available federal datasets, with a Data Coverage level of Very High. This reflects how much public data is available about a provider. How we calculate this →
Summary
Dr. Holtzman is a mixed practice specialist, with above-average Medicare volume (top 7% in MI), with speaking/promotional industry engagement in the top 7% of MI peers, with 19 years of NPI registration.
This summary is auto-generated from federal data, describing data availability and patterns. Read our methodology →
Frequently Asked Questions
Is Dr. Holtzman experienced with botox injection, per unit?
Based on Medicare claims data, Dr. Holtzman performed 10,300 botox injection, per unit services. Research suggests that higher procedure volume is often associated with better outcomes, particularly for complex procedures. Note that Medicare data only captures patients aged 65 and older, so the total practice volume across all patients is likely higher.
Does Dr. Holtzman receive payments from pharmaceutical companies?
Yes. Dr. Holtzman received a total of $1,527,753 from 110 companies across 4,368 individual payments. These payments are legal, publicly disclosed under the federal Sunshine Act, and common among physicians — 57% of all U.S. physicians receive at least one industry payment. Patients may wish to ask their doctor about these relationships, especially if a recommended drug or device appears in the payment records.
How do Dr. Holtzman's costs compare to other clinical neurophysiology physicians in Wayne?
Dr. Holtzman's average Medicare payment per service is $11. Note that these figures represent what Medicare pays, not your out-of-pocket cost, which depends on your specific insurance plan and deductible. Procedure-level data above shows both what was submitted and what Medicare paid for each service type.
What does Data Coverage mean?
Data Coverage (currently Very High for Dr. Holtzman) measures how much public federal data is available about a provider. It is not a quality rating. A "Very High" or "High" level means the provider has data across multiple federal sources (NPPES, PECOS, Medicare Utilization, Open Payments), indicating a long track record of practice, Medicare participation, and industry disclosure. A "Low" or "Moderate" level may simply mean the provider is newer, does not see Medicare patients, or has not received any industry payments — none of which are inherently negative. Read our full methodology →
Is this data up to date?
Each data source has its own update cycle. Provider registry data (NPPES) is updated weekly. Medicare enrollment (PECOS) is updated monthly. Medicare practice data has a ~2 year lag — the most recent available is typically 2 years prior. Industry payment data (Open Payments) is published annually, usually in June, covering the prior calendar year. We display the data date prominently on each section so you always know how current it is. See our data freshness policy →
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About this page
All data on this page is sourced verbatim from public federal records published by the U.S. Centers for Medicare & Medicaid Services (CMS): NPPES ↗, Open Payments ↗, Medicare Provider Utilization ↗, and PECOS. Publication is mandated by the Physician Payments Sunshine Act (§6002 ACA, 42 U.S.C. §1320a-7h) and the Freedom of Information Act.
This page is not medical advice, an endorsement, a recommendation, or a quality rating. Data Coverage reflects data completeness — how much federal information exists for this provider — not clinical performance, patient outcomes, or quality of care. Always verify information directly with the provider and consult a licensed clinician before making medical decisions.
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