Dr. Manuel Santiago, MD
What this data tells you about Dr. Santiago
Dr. Manuel Santiago is a hematology & oncology specialist in San Antonio, TX, with 20 years of NPI registration. Based on federal Medicare data, Dr. Santiago performed 44,847 Medicare services across 2,816 unique beneficiaries.
Between the years covered by Open Payments, Dr. Santiago received a total of $4,416 from 25 pharmaceutical and/or device companies across 66 individual payments. These payments are legal, publicly disclosed under the federal Sunshine Act, and common in hematology & oncology. Most payments are for meals and travel — low-value interactions common across virtually all practicing physicians. Patients may wish to discuss these relationships with their provider.
The Data Coverage level for Dr. Santiago is Very High — reflecting how much public federal data is available about this provider. This is not a quality rating. Patients are encouraged to use this data as one of several factors when choosing a healthcare provider.
Medicare Practice Summary
Medicare Utilization ↗Top procedures by volume
Ranked by number of services performed for Medicare patients. Avg. submitted charge is what the provider billed; avg. Medicare payment is what CMS paid.
| Procedure | Volume | Avg. paid | Avg. submitted |
|---|---|---|---|
| Iron infusion (Feraheme) | 15,810 | $0 | $5 |
| Azacitidine chemotherapy injection | 9,700 | $0 | $13 |
| Darbepoetin injection (Aranesp) for anemia | 6,350 | $2 | $20 |
| Contrast dye for imaging (iodine-based) | 4,762 | $0 | $3 |
| Injection, bortezomib, 0.1 mg | 1,330 | $4 | $116 |
| Blood draw (venipuncture) | 702 | $8 | $20 |
| Comprehensive metabolic blood panel | 684 | $10 | $64 |
| Complete blood count (CBC) with differential | 675 | $8 | $36 |
| Office visit, established patient (30-39 min) | 495 | $87 | $368 |
| Injection, granisetron hydrochloride, 100 mcg | 440 | $0 | $24 |
| Lactate dehydrogenase (enzyme) level | 332 | $6 | $31 |
| Dexamethasone injection (steroid) | 316 | $0 | $1 |
| Measurement of immunoglobulin light chains | 238 | $17 | $60 |
| Ferritin level test (iron stores) | 222 | $13 | $60 |
| Iron level test | 221 | $6 | $27 |
| Iron binding capacity test | 221 | $8 | $35 |
| Anti-nausea injection (Aloxi/palonosetron) | 190 | $1 | $114 |
| Immunoglobulin level test | 174 | $9 | $56 |
| Office visit, established patient (20-29 min) | 162 | $63 | $250 |
| Administration of chemotherapy into vein, 1 hour or less | 120 | $96 | $707 |
| Reticulated (young) platelet measurement | 108 | $35 | $143 |
| Infusion into a vein for therapy, prevention, or diagnosis, additional sequential infusion, 1 hour or less | 104 | $21 | $157 |
| Administration of non-hormonal anti-neoplastic chemotherapy under skin or into muscle | 101 | $54 | $211 |
| Red blood count automated, with additional calculations | 100 | $5 | $26 |
| Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less | 94 | $47 | $313 |
| Injection, zoledronic acid, 1 mg | 87 | $6 | $431 |
| Protein measurement, serum | 85 | $9 | $75 |
| Hospital follow-up visit, moderate complexity | 79 | $60 | $247 |
| Prothrombin time test (blood clotting) | 74 | $4 | $30 |
| Hospital follow-up visit, high complexity | 74 | $90 | $357 |
| Drug injection, under skin or into muscle | 72 | $10 | $96 |
| Carcinoembryonic antigen (cea) protein level | 65 | $19 | $99 |
| Immunologic analysis technique on serum (immunofixation) | 64 | $10 | $87 |
| New patient office visit (45-59 min) | 61 | $109 | $565 |
| Beta-2 microglobulin (protein) level | 54 | $16 | $96 |
| Injection of additional new drug or substance into vein | 49 | $12 | $108 |
| Infusion into a vein for therapy, prevention, or diagnosis, each additional hour | 43 | $16 | $100 |
| Sed rate test (inflammation marker) | 37 | $3 | $36 |
| Microscopic examination for white blood cells with manual cell count | 34 | $4 | $22 |
| Complete blood count (CBC), automated | 34 | $6 | $34 |
| Irrigation of implanted venous access drug delivery device | 30 | $16 | $114 |
| Injection, diphenhydramine hcl, up to 50 mg | 30 | $1 | $7 |
| Ct scan of chest with contrast | 28 | $49 | $821 |
| Coagulation function measurement, d-dimer; quantitative | 27 | $10 | $129 |
| CT scan of abdomen and pelvis with contrast | 25 | $170 | $1,067 |
| Vitamin B-12 level test | 24 | $15 | $76 |
| Ct scan of abdomen with contrast | 23 | $127 | $793 |
| Immunologic analysis for detection of tumor antigen, quantitative; ca 15-3 | 22 | $20 | $128 |
| Office visit, established patient, complex (40-54 min) | 21 | $123 | $496 |
| Urinalysis with microscopic exam | 16 | $3 | $28 |
| Folic acid level test | 13 | $14 | $73 |
| Administration of additional new drug or substance into vein, 1 hour or less | 13 | $45 | $344 |
| Initial hospital admission, moderate complexity | 12 | $89 | $470 |
Industry Payment Transparency
Open Payments through 2024 ↗Payment profile
Industry payments classified by relationship type. Not all payments are equal — research and consulting reflect different relationships than speaking programs or meals.
Payment trend by year
Annual totals from pharmaceutical and medical device companies.
Payments by company (2024)
Associated products mentioned in payments ›
Most payments (68%) are for meals and travel — low-value interactions that are common across virtually all practicing physicians.
Geographic Context
0.0 mi
Data Sources
| Provider Registry | ✓ NPPES | Weekly updates |
| Medicare Enrollment | ✓ PECOS | Monthly updates |
| Practice Data | ✓ Medicare Util. | Annual (CY lag) |
| Industry Payments | ✓ Open Payments | CY 2024 |
| Disciplinary History | — Not public | N/A |
This provider has data in 4 of 4 available federal datasets, with a Data Coverage level of Very High. This measures how much public data is available about a provider — not how good they are. How we calculate this →
Summary
Dr. Santiago is a mixed practice specialist, with above-average Medicare volume (top 21% in TX), with low-engagement industry engagement, with 20 years of NPI registration.
This summary is auto-generated from federal data. It describes data availability and patterns — not clinical quality. Read our methodology →
Frequently Asked Questions
Is Dr. Santiago experienced with iron infusion (feraheme)?
Does Dr. Santiago receive payments from pharmaceutical companies?
How do Dr. Santiago's costs compare to other hematology & oncology specialists in San Antonio?
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All data on this page is sourced verbatim from public federal records published by the U.S. Centers for Medicare & Medicaid Services (CMS): NPPES ↗, Open Payments ↗, Medicare Provider Utilization ↗, and PECOS. Publication is mandated by the Physician Payments Sunshine Act (§6002 ACA, 42 U.S.C. §1320a-7h) and the Freedom of Information Act.
This page is not medical advice, an endorsement, a recommendation, or a quality rating. The Transparency Score measures data completeness — how much federal information exists for this provider — not clinical performance, patient outcomes, or quality of care. Always verify information directly with the provider and consult a licensed clinician before making medical decisions.
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