Medicare Enrolled
Dr. Ryan Holstead, MD
Hematology & Oncology · Worcester, MA
Practice pattern: Mixed Practice
— Diverse clinical practice across multiple procedure types
Low-engagement
Very High
DATA COVERAGE
Data in 4 of 4 federal sources
Measures public federal data availability — not provider quality
Informational, not a quality rating.
This page presents federal public records about Dr. Holstead from CMS (NPPES, Open Payments, Medicare Provider Utilization, PECOS). It is not medical advice, an endorsement, or a judgment of clinical quality. Always consult the provider directly and a licensed clinician for medical decisions. Read methodology →
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What this data tells you about Dr. Holstead
Dr. Ryan Holstead is a hematology & oncology specialist in Worcester, MA, with 10 years of NPI registration. Based on federal Medicare data, Dr. Holstead performed 43,618 Medicare services across 4,396 unique beneficiaries.
Between the years covered by Open Payments, Dr. Holstead received a total of $1,164 from 23 pharmaceutical and/or device companies across 41 individual payments. These payments are legal, publicly disclosed under the federal Sunshine Act, and common in hematology & oncology. Most payments are for meals and travel — low-value interactions common across virtually all practicing physicians. Patients may wish to discuss these relationships with their provider.
The Data Coverage level for Dr. Holstead is Very High — reflecting how much public federal data is available about this provider. Patients are encouraged to use this data as one of several factors when choosing a healthcare provider.
✓ 10 years in practice
▲ Top 3% volume in MA
$1,164 industry payments
Medicare Practice Summary
Medicare Utilization ↗43,618
Medicare services
Top 3% in MA for hematology & oncology
4,396
Unique beneficiaries
$6
Avg. Medicare payment
Medicare patients only (65+ / disabled) · How to read this →
~4,362 Medicare services per year of practice
Top procedures by volume
Ranked by number of services performed for Medicare patients. Avg. submitted charge is what the provider billed; avg. Medicare payment is what CMS paid.
| Procedure | Volume | Avg. paid | Avg. submitted |
|---|---|---|---|
| Iron infusion (Injectafer) An intravenous injection of ferric carboxymaltose, an iron replacement medication. |
33,750 | $1 | $5 |
| Blood draw (venipuncture) Insertion of a needle into a vein to collect a blood sample. |
944 | $8 | $20 |
| Complete blood count (CBC) with differential An automated laboratory test that measures the levels of red blood cells, white blood cells, and platelets in the blood, including a breakdown of the different types of white blood cells. |
908 | $8 | $150 |
| Comprehensive metabolic blood panel A blood test that measures a group of chemicals, including glucose, electrolytes, and kidney and liver function markers. |
835 | $10 | $60 |
| Office visit, established patient (30-39 min) A follow-up office visit for an existing patient lasting between 30 and 39 minutes. The visit involves medical evaluation and management of the patient's condition. |
782 | $105 | $456 |
| Denosumab injection (Prolia/Xgeva) | 780 | $18 | $122 |
| Dexamethasone injection (steroid) An injection of dexamethasone sodium phosphate, a corticosteroid medication, administered in a dose of 1 milligram. |
587 | $0 | $10 |
| Flow cytometry, additional marker An additional marker is tested during a flow cytometry procedure to analyze DNA or cells. This step adds specific data points to the initial analysis. |
460 | $23 | $108 |
| Iron level test | 285 | $6 | $70 |
| Iron binding capacity test A blood test that measures the amount of iron in the blood and the blood's ability to bind and transport iron. |
284 | $8 | $125 |
| Ferritin level test (iron stores) A blood test that measures the level of ferritin, a protein that stores iron in the body. |
283 | $13 | $150 |
| Lactate dehydrogenase (LDH) level test A blood test that measures the amount of lactate dehydrogenase, an enzyme found in many body tissues. It helps assess tissue damage or disease. |
274 | $6 | $30 |
| Chronic care management, first 20 min/month This service covers the first 20 minutes of clinical staff time directed by a healthcare professional each calendar month to manage chronic conditions. |
273 | $53 | $150 |
| Vitamin B-12 level test A blood test that measures the amount of vitamin B-12 in your body. |
242 | $15 | $75 |
| Magnesium level test A blood test to measure the amount of magnesium in your body. This helps check for magnesium deficiency or excess. |
241 | $7 | $75 |
| Phosphate level test A blood test that measures the amount of phosphate in your body. Phosphate is a mineral that helps keep bones and teeth strong. |
234 | $5 | $50 |
| Immunoglobulin level test A blood test that measures the level of gammaglobulins, which are immune system proteins. |
214 | $9 | $45 |
| Hospital follow-up visit, moderate complexity Follow-up hospital visit for an existing patient involving moderate medical decision making. The visit requires at least 35 minutes of time spent on the date of service. |
192 | $70 | $201 |
| Carcinoembryonic antigen (CEA) level test A blood test that measures the level of carcinoembryonic antigen (CEA) protein. This test is used to monitor certain types of cancer. |
174 | $19 | $60 |
| Drug injection, under skin or into muscle A procedure involving the administration of a medication or substance via injection into the subcutaneous tissue or muscle. |
170 | $12 | $190 |
| Uric acid level test A blood test that measures the level of uric acid in your body. Uric acid is a waste product formed when the body breaks down purines. |
156 | $4 | $50 |
| Thyroid stimulating hormone (TSH) test A blood test that measures the level of thyroid stimulating hormone to evaluate thyroid function. |
108 | $16 | $150 |
| Immunoglobulin light chain measurement A blood test that measures the levels of immunoglobulin light chains, which are proteins produced by plasma cells. |
100 | $17 | $70 |
| Intravenous injection of additional new drug or substance Administration of an additional new medication or substance directly into a vein. |
96 | $15 | $95 |
| Immunologic analysis for detection of tumor antigen, quantitative; ca 15-3 | 93 | $20 | $70 |
| Office visit, established patient, complex (40-54 min) An office or outpatient visit for an existing patient lasting between 40 and 54 minutes. This level of service is determined by the total time spent on the date of the encounter. |
90 | $156 | $885 |
| Intravenous chemotherapy infusion, 1 hour or less Administration of chemotherapy medication directly into a vein. The procedure takes one hour or less to complete. |
86 | $129 | $550 |
| Vitamin D level test A blood test to measure the amount of Vitamin D-3 in your body. |
82 | $29 | $150 |
| Manual red blood cell count A laboratory test that manually counts the number of red blood cells in a blood sample. |
70 | $4 | $15 |
| Hemoglobin A1c test (diabetes monitoring) A blood test that measures your average blood sugar levels over the past two to three months. |
68 | $9 | $50 |
| Serum protein measurement A blood test that measures the total amount of protein in the serum. It helps evaluate overall health and nutritional status. |
62 | $10 | $60 |
| Additional sequential IV infusion, 1 hour or less This code represents an additional intravenous infusion administered sequentially to a primary infusion. It covers the administration time of one hour or less. |
57 | $28 | $120 |
| Vitamin B-12 injection An injection of vitamin B-12 (cyanocobalamin) with a dose of up to 1000 mcg. |
55 | $1 | $10 |
| Erythrocyte sedimentation rate (ESR) test A blood test that measures how quickly red blood cells settle in a test tube to detect inflammation in the body. This specific method is performed manually rather than using an automated machine. |
53 | $4 | $20 |
| PSA test (prostate cancer screening) | 49 | $18 | $50 |
| Intravenous drug injection A procedure involving the administration of a medication or substance directly into a vein. |
48 | $36 | $190 |
| Folic acid level test A blood test that measures the amount of folic acid in the serum. |
36 | $14 | $70 |
| Intravenous infusion, 1 hour or less Administration of medication or fluid directly into a vein for therapeutic, preventive, or diagnostic purposes. The procedure lasts one hour or less. |
36 | $63 | $500 |
| Additional hour of intravenous chemotherapy This code represents the administration of chemotherapy medication into a vein for each additional hour beyond the initial period. |
31 | $27 | $125 |
| Diphenhydramine injection, up to 50 mg An injection of diphenhydramine hydrochloride, an antihistamine medication, administered in a dose of up to 50 milligrams. |
31 | $1 | $10 |
| Serum immunofixation test A laboratory test that analyzes a blood serum sample to identify specific abnormal proteins. The procedure uses an immunologic technique to detect and characterize these proteins. |
28 | $21 | $110 |
| Office visit, established patient (20-29 min) An office visit for an existing patient lasting between 20 and 29 minutes. The visit involves medical evaluation and management of the patient's condition. |
27 | $73 | $300 |
| Immunologic analysis for detection of tumor antigen, quantitative; ca 125 | 26 | $20 | $50 |
| Additional hour of intravenous hydration This code represents each additional hour of intravenous fluid administration beyond the initial hour. It is used to bill for extended hydration therapy. |
26 | $12 | $80 |
| Initial hospital admission, moderate complexity Initial hospital inpatient or observation care for a new patient involving moderate-level medical decision making, with at least 55 minutes total time on the date of the encounter. |
23 | $106 | $422 |
| Prothrombin time test (blood clotting) A laboratory test that measures how long it takes for blood to clot. This procedure evaluates the body's coagulation process. |
20 | $4 | $30 |
| Flow cytometry DNA or cell analysis, first marker A laboratory test that uses a laser to analyze cells or DNA by detecting a specific marker on the cell surface or within the cell. |
20 | $74 | $300 |
| Beta-2 microglobulin level test A blood test that measures the level of beta-2 microglobulin, a protein produced by cells in the body. |
17 | $16 | $50 |
| New patient office visit (45-59 min) An initial office visit for a new patient lasting between 45 and 59 minutes. This code covers the total time spent by the physician or qualified healthcare professional on the date of the encounter. |
17 | $135 | $595 |
| Thyroxine (T4) level test A blood test that measures the total amount of thyroxine, a thyroid hormone, in your body. |
16 | $7 | $35 |
| Total testosterone level test A blood test that measures the total amount of testosterone in your body. This hormone is important for various bodily functions in both men and women. |
15 | $25 | $300 |
| Haptoglobin level test A blood test that measures the amount of haptoglobin, a protein in the serum. It helps evaluate red blood cell breakdown. |
14 | $12 | $75 |
| Initial hospital admission, high complexity Initial hospital inpatient or observation care for a new patient involving high-level medical decision making, with at least 75 minutes total time on the date of the encounter. |
14 | $146 | $612 |
| Thyroid hormone evaluation A blood test to measure the levels of thyroid hormones in the body. This evaluation helps assess how well the thyroid gland is functioning. |
13 | $6 | $20 |
| Lipid panel (cholesterol and triglycerides) A blood test that measures cholesterol and triglyceride levels. |
12 | $13 | $300 |
| Total bilirubin level test A blood test that measures the total amount of bilirubin, a waste product from the breakdown of red blood cells, in your body. |
11 | $5 | $15 |
How to read this data: This reflects Medicare patients only (typically 65+). Payment amounts are what Medicare paid the provider, not your out-of-pocket cost. A higher procedure volume generally indicates more experience with that procedure.
77.8% high complexity
4.1% medium
18.1% routine
Industry Payment Transparency
Open Payments through 2024 ↗$1,164
Total received (2021-2024)
Avg $291/year across 4 years
Top 47% in MA for hematology & oncology
A higher payment rank reflects disclosed industry relationships (consulting, research, speaking) common among subspecialists — not wrongdoing.
23
Companies
41
Individual payments
All payments are legal and publicly reported · Not evidence of wrongdoing · How to interpret →
Payment profile
Industry payments classified by relationship type. Not all payments are equal — research and consulting reflect different relationships than speaking programs or meals.
Meals & Travel
Food, beverages, travel, and lodging — typically low-value
$1,151 (98.9%)
Speaking / Promotional
Speaker programs, honoraria, and industry-sponsored educational events
$13 (1.1%)
Payment trend by year
Annual totals from pharmaceutical and medical device companies.
2024
$167
2023
$144
2022
$376
2021
$478
Payments by company (2024)
Consulting
Speaking
Meals & Travel
Research
Galvanize Therapeutics, Inc
$167
Top 3 companies account for 100.0% of 2024 payments
All-time payments by company (2021-2024) ›
E.R. Squibb & Sons, L.L.C.
$188
Celgene Corporation
$173
Galvanize Therapeutics, Inc
$167
Amgen Inc.
$164
Novartis Pharmaceuticals Corporation
$82
PFIZER INC.
$37
Janssen Biotech, Inc.
$31
Seagen Inc.
$30
PUMA BIOTECHNOLOGY, INC.
$26
Pharmacyclics LLC, An AbbVie Company
$25
Blue Earth Diagnostics Limited
$25
Ipsen Biopharmaceuticals, Inc
$24
Incyte Corporation
$22
Global Blood Therapeutics, Inc.
$21
SUN PHARMACEUTICAL INDUSTRIES INC.
$21
Karyopharm Therapeutics Inc.
$20
Boehringer Ingelheim Pharmaceuticals, Inc.
$18
GENZYME CORPORATION
$16
GlaxoSmithKline, LLC.
$16
Genentech USA, Inc.
$16
Exelixis Inc.
$15
Takeda Pharmaceuticals U.S.A., Inc.
$14
Bayer HealthCare Pharmaceuticals Inc.
$13
Top 3 companies account for 45.3% of all-time payments
Associated products mentioned in payments ›
ADCETRIS · ALIYA SYSTEM · Axumin · Cabometyx · ERLEADA · EXKIVITY · GILOTRIF · IMBRUVICA · JEVTANA · KISQALI · Kyprolis · LUMAKRAS · MONJUVI · NERLYNX · Nplate · Nubeqa · OPDIVO · OPDUALAG · OXBRYTA · Phesgo · Pomalyst · REBLOZYL · SOMATULINE DEPOT · TABRECTA · XPOVIO · XTANDI · YONSA · ZEJULA
Should you be concerned? Payments from pharmaceutical and device companies are legal and common — 57% of U.S. physicians receive at least one. They often reflect legitimate consulting, research, or education. What matters is whether a recommended drug or device appears in your doctor's payment records. If so, consider asking your doctor about it. How to interpret this data →
Most payments (99%) are for meals and travel — low-value interactions that are common across virtually all practicing physicians.
Data Sources
| Provider Registry | ✓ NPPES | Weekly updates |
| Medicare Enrollment | ✓ PECOS | Monthly updates |
| Practice Data | ✓ Medicare Util. | Annual (CY lag) |
| Industry Payments | ✓ Open Payments | CY 2024 |
| Disciplinary History | — Not public | N/A |
This provider has data in 4 of 4 available federal datasets, with a Data Coverage level of Very High. This reflects how much public data is available about a provider. How we calculate this →
Summary
Dr. Holstead is a mixed practice specialist, with above-average Medicare volume (top 3% in MA), with low-engagement industry engagement.
This summary is auto-generated from federal data, describing data availability and patterns. Read our methodology →
Frequently Asked Questions
Is Dr. Holstead experienced with iron infusion (injectafer)?
Based on Medicare claims data, Dr. Holstead performed 33,750 iron infusion (injectafer) services. Research suggests that higher procedure volume is often associated with better outcomes, particularly for complex procedures. Note that Medicare data only captures patients aged 65 and older, so the total practice volume across all patients is likely higher.
Does Dr. Holstead receive payments from pharmaceutical companies?
Yes. Dr. Holstead received a total of $1,164 from 23 companies across 41 individual payments. These payments are legal, publicly disclosed under the federal Sunshine Act, and common among physicians — 57% of all U.S. physicians receive at least one industry payment. Patients may wish to ask their doctor about these relationships, especially if a recommended drug or device appears in the payment records.
How do Dr. Holstead's costs compare to other hematology & oncology specialists in Worcester?
Dr. Holstead's average Medicare payment per service is $6. Note that these figures represent what Medicare pays, not your out-of-pocket cost, which depends on your specific insurance plan and deductible. Procedure-level data above shows both what was submitted and what Medicare paid for each service type.
What does Data Coverage mean?
Data Coverage (currently Very High for Dr. Holstead) measures how much public federal data is available about a provider. It is not a quality rating. A "Very High" or "High" level means the provider has data across multiple federal sources (NPPES, PECOS, Medicare Utilization, Open Payments), indicating a long track record of practice, Medicare participation, and industry disclosure. A "Low" or "Moderate" level may simply mean the provider is newer, does not see Medicare patients, or has not received any industry payments — none of which are inherently negative. Read our full methodology →
Is this data up to date?
Each data source has its own update cycle. Provider registry data (NPPES) is updated weekly. Medicare enrollment (PECOS) is updated monthly. Medicare practice data has a ~2 year lag — the most recent available is typically 2 years prior. Industry payment data (Open Payments) is published annually, usually in June, covering the prior calendar year. We display the data date prominently on each section so you always know how current it is. See our data freshness policy →
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About this page
All data on this page is sourced verbatim from public federal records published by the U.S. Centers for Medicare & Medicaid Services (CMS): NPPES ↗, Open Payments ↗, Medicare Provider Utilization ↗, and PECOS. Publication is mandated by the Physician Payments Sunshine Act (§6002 ACA, 42 U.S.C. §1320a-7h) and the Freedom of Information Act.
This page is not medical advice, an endorsement, a recommendation, or a quality rating. Data Coverage reflects data completeness — how much federal information exists for this provider — not clinical performance, patient outcomes, or quality of care. Always verify information directly with the provider and consult a licensed clinician before making medical decisions.
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